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In Vitro Testing of an Ethanol Collection Method Combining Particulate and Gas-Vapor Phase Components: Bacterial Reversion Mutation (Ames) Assay

TSRC 2019

Determining the impact of flavored e-liquids on aldehyde production during Vaping

Details a framework for assessing the impact of flavored formulations on the production of carbonyl compounds in Aerosol. Describes the impact of device variability on the formation of acetaldehyde, acrolein, and formaldehyde in ENDS Aerosol.

How-to Video: Soil-Vapor Sampling – Shroud Setup

In this video, learn how to properly perform soil-vapor sampling using the hard-body shroud, purge can, and detectors…

How-to Video: Soil-Vapor Sampling – Large-Scale Mobilizations

When logistics are made more difficult by several well points and require a large amount of gear, this video will demonstrate how to properly perform soil-vapor sampling…

How-to Video: Soil-Vapor Sampling – Helium-Shroud Sampling

In this video, learn how to properly set up and break down the hard-body shroud and helium detectors when taking a purge of a sample well.

How-to Video: Soil-Vapor Sampling – Sampling for DTSC Site Closure

This video will demonstrate how to properly test for soil-vapor in low-porosity, low-volume conditions such as sand, silt or clay.

The impact of FDA regulation, a CRO’s perspective on changes in the industry

The signing of the Tobacco Control Act (TCA) on June 22, 2009 caused far reaching and permanent changes to the regulation and testing of tobacco products in the US.

Reference product characterization

This presentation will focus on how reference and/or monitor tobacco products are characterized and then used by analytical testing facilities to assure method performance during the analysis of tobacco products.

Optimization of an analytical method for the determination of PAHs in tobacco and tobacco smoke by GC-MS

Polycyclic aromatic hydrocarbons (PAHs) are an extensive group of compounds formed as a result of incomplete combustion of carbonaceous materials and are known components in mainstream…

Neutral red uptake cytotoxicity assay in A549 cells under different culture conditions

The OECD guideline (TG129) recommends mouse fibroblasts (3T3) & normal human epidermal keratinocytes (NHK) for performing in vitro cytotoxicity assays but also mentions limitations of these cells, such as having little to no metabolic…

Neutral red uptake (NRU) cytotoxicity analysis of aerosol generated from a temperature-regulated nicotine-salt based ends product

JUUL ENDS is a temperature-regulated product which was designed to minimize the generation of combustion related…

Machine made cigar leaf and product workshop

The regulation of tobacco products continues to be a growing focus around the world.

Evaluation of an online, puff-by-puff method for the determination of nitric oxide, nitrogen dioxide, and total mono-nitrogen oxides in fresh mainstream smoke

The amount of nitric oxide (NO), nitrogen dioxide (NO2) and total mono-nitrogen oxides (NOx) in mainstream smoke is of…

Effect of power level on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols

The study objective was to determine the effect of power applied to the atomizer of refillable tank-based e-cigarette (EC) devices.

E-cigarette Workshop

This workshop will be presented in two parts. The first section will focus on the basic design and construction of both typical disposable/rechargeable devices and selected advanced personnel vaporizers.

Do temperature regulated e-cigarettes prevent the formation of thermal decomposition products under dry wick conditions?

The study objective was to determine if temperature regulated e-cigarette (TR-EC) devices could reduce the formation of thermal decomposition products under…

Development, validation and routine use of a method for the determination of carbonyl compounds in cigar smoke

The U.S. Food and Drug Administration recently finalized a rule that extends its regulatory authority to all tobacco products including cigars.

Determination of aromatic amines through the use of tandem mass spectrometry coupled to gas phase chromatography

The number of compounds of regulatory interest in cigarette smoke has increased in recent years.

Characterization of a temperature regulated e-cigarette for potential use as a reference device

The development and adoption of a well characterized reference e-cigarette would be useful during the routine analysis of e-cigarette emissions.

Are chemical constituents exhaled in a room where e-vapor products are used?

A controlled clinical study was conducted to determine potential constituents in the atmosphere where e-vapor products and cigarettes were used.

Application and use of e-cigarettes HPHC methods for the analysis of heated tobacco products

The interest in e-cigarette research has resulted in the development of methods for quantitative analysis of chemical constituents present in their aerosols.

Analysis of nitrosamine content, moisture, and pH in pouched smokeless tobacco products: a comparison of constituents in the intact product, tobacco and pouching material

The purpose of this study was to determine if water content, pH and…

Ames assay cytotoxic assessment using bacterial lawn integrity with 35 mm plate spread technique

The Ames assay is commonly used to evaluate the mutagenic potential of tobacco products for regulatory purposes…

Comparison of the Yield of Very Low Nicotine Content Cigarettes to the Top 100 United States Brand Styles

The objective of this work was to compare the nicotine content and yield of new very low nicotine content cigarettes (VLN™) to the top 100 cigarette brand styles in the United States.

Comparative Levels of Carbonyl Delivery Between Mass-Market Cigars and Cigarettes

See this peer reviewed article by I. Gene Gillman in the journal of Regulatory Toxicology and Pharmacology

Site-Specific Sediment Criteria: A framework for using bioassays as a tool for risk assessments

When to use bioassays as a tool for risk assessments

Proton Transfer Reaction Mass Spectrometry (PTR-MS) for Ambient and (Compliance) Source Testing Discussion

Our research on the capabilities of proton transfer reaction time of flight mass spectrometry (PTR-MS) as a real-time measurement instrument.

Optimization of EPA Method TO-15 for Analysis of ppt Levels of Ethylene Oxide in Ambient Air

Learn how we optimized EPA Method TO-15 to achieve a 10 ppt reporting limit for ethylene oxide.

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